A Process for Engineer Domain Ontology: An Experience in Developing Business Analysis Ontology

During the last years several works have been aimed to improve ontology technological as-pects, like representation language and inference mechanisms. This paper presents a discussion on the process and product of an experience in developing ontology for the public sector whose organization requires a strong knowledge management. This process is applied to engineer and develop ontology for Business analysis domain.Ontology, Ontology Engineering, Methodology, Protégé, Business Analysis

A Process for Engineer Domain Ontology: An Experience in Developing Business Analysis Ontology

During the last years several works have been aimed to improve ontology technological as-pects, like representation language and inference mechanisms. This paper presents a discussion on the process and product of an experience in developing ontology for the public sector whose organization requires a strong knowledge management. This process is applied to engineer and develop ontology for Business analysis domain

Što na početku prvoga razreda učenici znaju i mogu iz područja matematike – je li to važno ili nije?

The determination of the levels of mathematical knowledge and skills is of essential importance when planning and organizing any form of work with students as well as in the process of creating mathematics curriculum. A question emerges: What kind of mathematical knowledge and skills are children equipped with when entering the first grade of primary school? In the Republic of Macedonia, written mathematics testing of children at this age (approximately 6 years) is not conducted. At the national level there are no data on this issue. At the beginning of the school year 2011/2012 a research study was conducted in primary schools in the Republic of Macedonia, based on a previous research conducted in the Netherlands. The results on five of the given problems are discussed and compared with the results obtained from similar studies conducted previously in other European countries. Another question consequently emerges: Does the national mathematics curriculum for the first grade give full credit to children\u27s actual mathematics competences and does it provide optimal conditions for their further advancement?Određivanje razina matematičkog znanja i vještina od ključne je važnosti prilikom planiranja i organiziranja rada s učenicima, kao i prilikom stvaranja kurikula iz područja matematike. Pitanje koje se postavlja jest: Kakvo znanje i vještine iz matematike posjeduju učenici na početku prvog razreda osnovne škole? U Republici Makedoniji ne provode se pismeni testovi iz matematike za šestogodišnjake. Na nacionalnoj razini ne postoje podatci povezani s tom problematikom. Na početku šk. god. 2011./2012. u Republici Makedoniji provedeno je istraživanje u osnovnim školama koje se oslanja na istraživanje u Nizozemskoj. Provedena je analiza rezultata i njihova usporedba s rezultatima sličnih istraživanja u europskim zemljama. Na kraju istraživanja postavlja se pitanje: Uzima li nacionalni kurikul za matematiku za prvi razred u obzir u potpunosti matematičku kompetenciju djece i pruža li im optimalne uvjete za daljnji napredak

Clinical Importance of Low Level of PAPP-A in First Trimester of Pregnancy - An Obstetrical Dilemma in Chromosomally Normal Fetus

BACKGROUND: A variety of recent evidence exists about the clinical implication of low level of Pregnancy-associated plasma protein A (PAPP-A) in pregnancy. This glycoprotein is a protease, which releases the Insulin-like growth factor from IGFBP 4. Its role is a trophoblastic invasion of decidua, stimulation of cell mitosis and differentiation. It has an immunosuppressive effect in the placenta, inhibition of coagulation and complex role for integration of all these processes in the placenta. Level of PAPP-A (under 0.4 MoM-Multiple of Medians) in first-trimester screening in chromosomally and morphologically normal fetuses, could influence fetal weight, preeclampsia, premature birth and stillbirth. As a result of the complications mentioned above, there is implication on timing, mode of delivery and condition of the newborn. AIM: The study aims to evaluate the influence of low PAPP-A, measured in the first trimester on the outcome of pregnancy, with accent disorders which are the result of placental insufficiency. Also, gestational week, mode of delivery and condition of newborn secondary underlying conditions will be evaluated. MATERIAL AND METHODS: After given information and consultation about the expectation from the screening, pregnant women with a singleton pregnancy were tested for First Trimester Screening to estimate the risk for Trisomy 21, 13, 18- the most frequent chromosomopathies. After exclusion of chromosomopathies and congenital malformations, one hundred and fourteen patients enrolled in the study. The target group (n = 64) with PAPP-A below 0.4 MoM and control group (n = 50) with PAPP-A equal and above 0.4 MoM. An assessment of mode and time of delivery and presence of small for gestational age newborns, preeclampsia, premature birth and newborn condition at delivery was made. RESULTS: The percentage of the patients delivered in term was similar between the target group (n = 64) and the control group (n = 50), 82.81% vs 82.0% respectively. The rate of cesarean section was 29.7 % in the target group vs 32% in the control group. A significant difference was found about elective vs urgent cesarean section in favour of the target group. The difference was present about the complication in pregnancy before delivery, 56% vs 22%, p = 0.023, which were the main indication for cesarean section. The difference in newborn outcome was not significant. CONCLUSION: There is a difference in frequency of complications, in the cases with PAPP-A under 0.4 MoM, such as premature birth, preeclampsia compound with SGA fetuses versus the control group. The difference for SGA newborn and premature birth among the groups has statistical significance. The patients delivered with cesarean section were with the main indications SGA or elevated blood pressure, often occurred combined with prematurity. Apgar score and birth weight were similar in target and control group, but the newborns with a birth weight under 2500 g. were more frequent in the target group. Because these results did not show another significance among two groups, probably lower cut-off is needed, combining with another test (Doppler of uterine arteries in the first trimester, biochemical test). Presence of other diseases which could hurt placental function should be emphasised

Obstetric Outcome in Pregnant Patients with Low Level of Pregnancy-Associated Plasma Protein A in First Trimester

BACKGROUND: Pregnancy-associated plasma protein A (PAPP-A), is a protease which releases Insulin-like growth factor. The role of this factor is stimulation of cell mitosis, differentiation and trophoblastic invasion of deciduas. Identification of patients with low PAPP-A (under 0.4 MoM in the first trimester has an influence on birth weight, attenuation of fetal growth, preeclampsia, birth and fetal demise.AIM: The main issue in the study is evaluating an influence of PAPP-A, calculated in the first trimester on the unfavourable outcome of pregnancy.MATERIAL AND METHODS: Seventy pregnant women with singleton pregnancy underwent first-trimester biochemical screening. The target group were women with PAPP-A below 0.4 MoM, and in control group, PAPP-A were оver 0.4 MoM. There was an assessment of the influence on the mode of delivery, gestational week, the presence of intrauterine growth restriction, preeclampsia, temporary birth, intrauterine fetal demise and newborn condition.RESULTS: In target group, consisted of 35 patients, 16 were delivered at term. From 28 to 37 g.w.- were 7 patient, 22-28 g.w.- 4 and 8 patients were under the 22 g.w (all with fetal demise) there were 19 pretemporary deliveries - 9 with Cesarean Section (SC). In the target group: 5 newborn wеre with IUGR, 6 women had preeclampsia, 1 had placental abruption. In control group were 35 patients: 28 delivered at term, 9 with SC, 26 vaginal deliveries; with IUGR were 4 newborns. Two newborns were hypertrophic.CONCLUSION: There is a significant difference in unfavourable outcome in the cases with PAPP-A under 0.4 Mom, particular in the group, with a PAPP-A value under 0.2 MoM. The patients delivered with SC with the main indications in utero hypoxia, growth restriction and elevated blood pressure had PAPP-A between 0.3-0.4 MoM. The patients with intrauterine fetal death and placental abruption in the most of the cases have PAPP-A value under 0.2 MoM. There is a need to be aware in these pregnancies to achieve the preventions of adverse outcome, to decrease perinatal morbidity and mortality

Healthcare Resort Krvavica

Die vorliegende Diplomarbeit befasst sich mit dem ehemaligen Kinderspital in der kroatischen Ortschaft Krvavica, einem Enwurf des Architekten Rikard Marasovic. Der Bau wurde für Kinder mit Lungenkrankheiten geschaffen. Die Eröffnung war 1965 und seitdem diente das Gebäude zehn Jahre lang seiner ursprünglichen Bestimmung. Später wurde es als Hotel genutzt und Ende der 1990er Jahre kam es seiner Funktion als Flüchtlingslager nach. Der heute verlassene Gebäudekomplex besteht aus drei Gebäuden - aus einem Hauptgebäude, einem Nebengebäude als Lagerhaus und aus einem Wohnhaus für das Personal. Ziel dieser Arbeit ist die Revitalisierung der Ruine, so dass die Nutzung als Gesundheitskomplex vor allem für Kinder, aber auch für Erwachsene mit Atemwegserkrankungen möglich ist. Als Erweiterung des auf Grund der besonderen Lage des Komplexes, könnte die Wiedernutzung des Komplexes nicht nur zur Genesung der Patienten und zum Wohlstand und Erholung der Begleitpersonen beitragen, sondern auch den Erholungstourismus und die damit verbundenen wirtschaftlichen Vorteile für Kroatien, verstärken. Weiters entsteht hier eine Hotelanlage für die Familienangehörigen der Patienten / Begleitpersonen und externe Besucher.The present diploma thesis deals with the former children’s hospital in the croatian village of Krvavica. The then hospital was designed by Architect Rikard Marasovic, and planned to accommodate children with various lung diseases. It began operation in 1965, and served as a hospital for only 10 years. It was then converted into a hotel, where its use changed to that of a refugee camp in the 90s. The now abandoned building complex consists of three buildings - a main building, an auxiliary building which served as a warehouse, and a tertiary building which served as a residential complex for the staff.The aim of this work is the revitalization of the abandoned complex, so that it can be used again as a health complex specialized for children, but also for adults, with respiratory complications. Part of the project is the design of a building extension which will serve as a hotel for the patients’ family members, escorts and other guests. Due to the singular location of the complex, the site’s repurposing and remodelling could contribute to the successful recovery of patients, and the psychological relaxation of their accompanying persons. In addition, it may very well strengthen recreational tourism and any associated economic advantages for Croatia.14

Implementation of subontology of Planning and control for business analysis domain

Ontologies are at the heart of the semantic web. They define the concepts and relationships that make global interoperability possible. However, as these ontologies grow in size they become more and more difficult to create, use, understand, maintain, transform and classify. As ontologies become common in more applications and as those applications become larger and longer-lived, it is becoming increasingly common for ontologies to be developed in different area of public sector of economics. Ontologies present special challenges to the problem of conceptual modeling. This paper describes the process of the implementation of a subontology of forecasting and evaluations for business analysis domain in order to develop an easy and correct way to find the needed statistical information in a knowledge base

Implementation of subontology of Planning and control for business analysis domain

Ontologies are at the heart of the semantic web. They define the concepts and relationships that make global interoperability possible. However, as these ontologies grow in size they become more and more difficult to create, use, understand, maintain, transform and classify. As ontologies become common in more applications and as those applications become larger and longer-lived, it is becoming increasingly common for ontologies to be developed in different area of public sector of economics. Ontologies present special challenges to the problem of conceptual modeling. This paper describes the process of the implementation of a subontology of forecasting and evaluations for business analysis domain in order to develop an easy and correct way to find the needed statistical information in a knowledge base.ontology, forecasting, assessment, Protege, implementation, Research and Development/Tech Change/Emerging Technologies, GA, IN,